Full entry information is:


SEARCHBreast Model IDSB_0001 (version 2)
Model Submission Date2014-04-23
Model TypeXenograft
Model NameMDA-MB-231 Bone Metastasis Model
Strain BALB/c-Nude
Sex Female
Site Intracardiac
Cell Line-
Material AvailableMice / Brain (-)
Material Storage -
Therapy Available Yes
Therapy Single dose day 2 after tumour cell injection - 2mg/kg doxor ubicin, 100ug/kg zoledronic acid, saline control, dox followed 24 later by zol. Animals culled day 15 and day 21.
Analyses Tumour volume; Apoptosis; Proliferation;
ReferenceBrown HK, Ottewell PD, Evans CA, Coleman RE, Holen I (2012) A single administration of combination therapy inhibits breast tumour progression in bone and modifies both osteoblast and osteoclasts. Journal of Bone Oncology, 1:47-56.
PubMed ID-
Additional References -
Additional References PubMed IDs-
Study Molecule -
Notes -

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