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SEARCHBreast Model IDSB_0025 (version 1)
Model Submission Date2015-01-13
Model TypeXenograft
Model Name-
Strain MF1 nude
Sex Female
Site Subcutaneous - flank
Cell LineMDA-MB-436
Material AvailableTumour (-)
Material Storage
TumourFFPE
Therapy Available Yes
Therapy Control (0.1mls PBS), 100ug/kg zoledronic acid, 2mg/kg doxorubicin or 100ug/kg zoledronic acid followed 24h later by 2mg/kg doxorubicin. All treatments were given once per week for 4 weeks
Analyses Tumour volume; Vascularisation; Apoptosis; Proliferation; Gene expression;
Reference14. Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer. Ottewell PD, Mönkkönen H, Jones M, Lefley DV, Coleman RE, Holen I. J Natl Cancer Inst. 2008 Aug 20;100(16):1167-78.
PubMed ID18695136
Additional References -
Additional References PubMed IDs-
Study Molecule -
Notes -

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