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SEARCHBreast Model IDSB_0040 (version 1)
Model Submission Date2015-01-26
Model TypeGEMM
Model Name MMTV-Cre
JAX Number No jax number
DescriptionThis transgenic strain expresses P1 Cre recombinase under the control of the MMTV LTR promoter. Used for mammary specific activation of conditional GEM alleles; hormonally regulated. Note there are various lines of MMTV-Cre with different phenotypes.
Common NamesMMTV-Cre
Strain FVB
Sex M/F mixed collection
Develops Mammary TumoursNot applicable
Preneoplastic Lesions -
Develops Metastasis No
ER No information provided
PR No information provided
HER2 No information provided
Origin -
CK5 No information provided
CK8 No information provided
p63 No information provided
SMA No information provided
Metastasis Site-
Metastasis Bone Penetrance -
Metastasis Brain Penetrance-
Metastasis Lung Penetrance -
Metastasis Liver Penetrance-
Material AvailableMice (-)
Material Storage
ReferenceAmplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis. Andrechek ER, Hardy WR, Siegel PM, Rudnicki MA, Cardiff RD, Muller WJ. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3444-9
PubMed ID10716706
Additional References -
Additional References PubMed IDs-
Therapy -
Genetic Studies-
Notes We have crossed this line with a reporter and have detailed information on Cre expression

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