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SEARCHBreast Model IDSB_0044 (version 1)
Model Submission Date2015-03-30
Model TypeGEMM
Model Name Blg-Cre
JAX Number No jax number
Descriptionbeta-lactoglobin driven Cre recombinase transgene used for mammary specific activation of conditional GEM alleles; hormonally regulated.
GEMM AlleleBlg-Cre
Common NamesBlg-Cre
Strain C57Bl/6
Sex M/F mixed collection
Develops Mammary TumoursNo
Preneoplastic Lesions No
Develops Metastasis No
ER No information provided
PR No information provided
HER2 No information provided
Origin -
CK5 No information provided
CK8 No information provided
p63 No information provided
SMA No information provided
CKOther-
Metastasis Site-
Metastasis Bone Penetrance -
Metastasis Brain Penetrance-
Metastasis Lung Penetrance -
Metastasis Liver Penetrance-
Material Available- (-)
Material Storage
MiceLive
Analyses-
ReferenceEfficient BLG-Cre mediated gene deletion in the mammary gland. Selbert S, Bentley DJ, Melton DW, Rannie D, Lourenço P, Watson CJ, Clarke AR. Transgenic Res. 1998 Sep;7(5):387-96.
PubMed ID9859227
Additional References Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. Chapman RS, Lourenco PC, Tonner E, Flint DJ, Selbert S, Takeda K, Akira S, Clarke AR, Watson CJ. Genes Dev. 1999 Oct 1;13(19):2604-16.
Additional References PubMed IDs10521404
Therapy -
Genetic Studies-
Notes -

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