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SEARCHBreast Model IDSB_0112 (version 1)
Model Submission Date2018-04-12
Model TypeGEMM
Model Name Blg-Cre
JAX Number No jax number
Descriptionbeta-lactoglobin driven Cre recombinase transgene used for mammary specific activation of conditional GEM alleles; hormonally regulated.
GEMM AlleleBlg-Cre
Common NamesBlg-Cre
Strain C57Bl/6
Sex M/F mixed collection
Develops Mammary TumoursYes
Preneoplastic Lesions No
Develops Metastasis Yes
ER Positive
PR Mixed positive and negative
HER2 Mixed positive and negative
Origin Luminal
CK5 Negative
CK8 Negative
p63 Negative
SMA Positive
CKOther-
Metastasis SiteBone; Brain; Lung;
Metastasis Bone Penetrance 0-100%
Metastasis Brain Penetrance0-40%
Metastasis Lung Penetrance 0-40%
Metastasis Liver Penetrance-
Material AvailableBrain / Bone / Other (-)
Material Storage
MiceLive
Mammary tumourFFPE
Mammary gland (preneoplastic)Frozen
Whole mammary gland (normal)Frozen
Mammary epithelial cellsFFPE
Lung metastasisOther
LiverOther
Lymph nodeOther
AnalysesTumour volume;
Reference-
PubMed ID-
Additional References -
Additional References PubMed IDs-
Therapy -
Genetic Studies-
Notes -

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